Model-based administration of inhalation anaesthesia. 1. Developing a system model
نویسندگان
چکیده
منابع مشابه
Model-based administration of inhalation anaesthesia. 1. Developing a system model.
This paper is the first of a series of reports on a system model for the administration of inhalation anaesthesia. We present the development and basic testing of the model. It is a multiple-gas model; it covers fresh-gas flow rates from basal to more than total ventilation and includes an actual, not an idealized, circle-absorber breathing system featuring a standing bellows ventilator. Kineti...
متن کاملModel-based administration of inhalation anaesthesia. 3. Validating the system model.
BACKGROUND We quantified the predictive performance of our computer model of the administration of inhalation anaesthesia from a Datex-Ohmeda Modulus CD circle-absorber system. METHODS In 50 patients, desflurane anaesthesia was maintained with a fresh-gas flow (FGF) of 0.5 litres min(-1) of both nitrous oxide and oxygen, preceded by fast (n=14) or slow (n=36) induction: FGF greater than total...
متن کاملModel-based administration of inhalation anaesthesia. 2. Exploring the system model.
We explored our model by displaying its new capabilities, testing its sensitivity to variations in input data and illustrating its use. Its multiple-gas character allows simulation of the mechanisms governing concentration and second gas effects. Simulating the volume of a standing bellows makes it possible to test algorithms for automated closed-circuit anaesthesia. Using desflurane, the model...
متن کاملModel-based administration of inhalation anaesthesia. 4. Applying the system model.
BACKGROUND We developed and tested a simple dosing strategy for rapid induction with isoflurane followed by maintenance under minimal-flow conditions, that is 0.5 litre min(-1) total fresh gas flow (FGF). An end-expired concentration was to be achieved within 5 min in a desired therapeutic window, that is 0.8-1.1 vol%, and to be maintained within it for at least 30 min. METHODS With our new m...
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over the past decades a number of approaches have been applied for forecasting mortality. in 1992, a new method for long-run forecast of the level and age pattern of mortality was published by lee and carter. this method was welcomed by many authors so it was extended through a wider class of generalized, parametric and nonlinear model. this model represents one of the most influential recent d...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2001
ISSN: 0007-0912
DOI: 10.1093/bja/86.1.12